Year: 2015 | Month: April | Volume 5 | Issue 1
Comparative Efficacy of different Antimicrobials Used in the Treatment of Colibacillotic Calves
Abstract:
Colibacillosis of newborn calves is characterised by rapid onset, watery white or yellowish diarrhoea and high mortality. In the present therapeutic study the efficacy of four highly sensitive in-vitro drugs viz., ciprofloxacin, gentamicin, neomycin and co-trimoxazole was evaluated. Ciprofloxacin at the dose rate of 4mg/kg body weight was found 100 per cent effective, gentamicin at the dose rate of 4mg/kg body weight was found 83.33 per cent effective where as neomycin @10mg/kg body weight and co-trimoxazole @ 25 mg/kg body weight were found 66.67 per cent effective in this study. Treatment regimen used in four different groups of clinical cases of colibacillosis indicated ciprofloxacin being most effective drug followed by gentamicin, neomycin and co-trimoxazole which was comparable with in-vitro studies.
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